منابع مشابه
Kidney : Nephroblastoma ( Wilms tumor )
Other names: Nephroblastoma Note: Wilms' tumor, although generally rare, is the most common abdominal malignancy in children. Wilms' tumor cells are believed to derive from pluripotent embyronic renal precursor cells. Thus, Wilms' tumors are linked to the early development of the kidney. While most are isolated sporadic tumors, approximately 10% of cases are associated with genetic syndromes an...
متن کاملAdult Nephroblastoma (Wilms Tumor): A Case Report
Nephroblastoma (Wilms tumor) is the most common primary malignant renal tumor in children. Rarely, it may present in the adult age group. This is a case report of a diagnosed case of a 29-yearold female presenting with right-sided flank pain and hematuria. Abdominal sonogram revealed a right renal mass measuring 1.55 × 1.88 × 1.62 cm on the lower pole of the right kidney. CT scan showed a 2.1 ×...
متن کاملImmunohistochemical expression of Wilms' tumor 1 protein in nephroblastoma.
BACKGROUND Approximately 10% of nephroblastomas (Wilms' tumors) carry mutations in the Wilms' tumor 1 (WT1) gene. Recently, a WT1 antibody raised against N-terminal 1-181 amino acids of human WT1 became commercially available for immunohistochemical use on paraffin-embedded tissue. The aim of this study was to investigate the diagnostic and prognostic value of WT1 N-terminal antibody in nephrob...
متن کاملWilms' Tumor in a Horseshoe Kidney
The incidence of horseshoe kidney is about 1 in 400 cases. The presence of Wilms' tumor with a horseshoe kidney is unusual, and the occurrence of Wilms' tumor in a horseshoe kidney is estimated at 0.4 to 0.9% of all Wilms' tumors. We report the case of a 5-year-old boy who presented with a stage IV Wilms' tumor in a horseshoe kidney. The patient was treated with preoperative chemotherapy follow...
متن کاملExpression and prognostic value of Wilms' tumor 1 and early growth response 1 proteins in nephroblastoma.
Wilms' tumor is one of the most common solid tumors of children. The protein product of the tumor-suppressor gene, Wilms' tumor 1 (WT-1), binds to the same DNA sequences as the protein product of the early growth response 1 (EGR-1) gene. There is experimental evidence that EGR-1 is involved in controlling cell growth. The expression of both genes in Wilms' tumor was studied by others, mainly at...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/38390